Protein mass spectrometry detects multiple bloodmeals for enhanced Chagas disease vector ecology

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dc.contributor.authorKeller, Judith I.
dc.contributor.authorLima-Cordón, Raquel
dc.contributor.authorMonroy, M. Carlota
dc.contributor.authorSchmoker, Anna M.
dc.contributor.authorZhang, Fan
dc.contributor.authorHoward, Alan
dc.contributor.authorBallif, Bryan A.
dc.contributor.authorStevens, Lori
dc.date.accessioned2019-09-05T16:12:34Z
dc.date.available2019-09-05T16:12:34Z
dc.date.issued2019-08-07
dc.description.abstractEcohealth-based approaches have been recognized as a sustainable method of Chagas disease control. Bloodmeal data and vector prevalence of various hosts fosters an understanding of local vector ecology and behavior. This detailed paper provides validation of the ability to detect multiple bloodmeals using synthetic hemoglobin reference peptides (SRPs) that differ among the previously reported most common bloodmeals. The study shows the superior ability of hemoglobin peptide-based LC-MS/MS to detect and identify Chagas disease vector bloodmeal sources (of field-collected Triatomine vectors from Guatemala), compared to classical DNA-based polymerase chain reaction (PCR).en
dc.format.mimetypeapplication/pdf
dc.identifier.issn1567-1348
dc.identifier.urihttp://hdl.handle.net/10625/57964
dc.language.isoen
dc.publisherElsevieren
dc.relation.journalInfection, Genetics and Evolution
dc.subjectECOHEALTHen
dc.subjectTRIATOMAen
dc.subjectCHAGAS DISEASEen
dc.subjectEPIDEMIOLOGYen
dc.subjectDISEASE VECTORSen
dc.subjectSPECTROMETRYen
dc.subjectTAXONOMYen
dc.subjectHEMOGLOBINen
dc.subjectGUATEMALAen
dc.subjectLATIN AMERICAen
dc.subjectNORTH AND CENTRAL AMERICAen
dc.titleProtein mass spectrometry detects multiple bloodmeals for enhanced Chagas disease vector ecologyen
dc.typeJournal Article (peer-reviewed)en
idrc.copyright.holder© 2019 Elsevier B.V.
idrc.copyright.oapermissionsourceMGC signed post January 2008en
idrc.dspace.accessOpen Accessen
idrc.project.componentnumber106531001
idrc.project.number106531
idrc.project.titleEcohealth Interventions for Chagas Disease Prevention in Central Americaen
idrc.recordsserver.bcsnumberIC36-1643402171-240995
idrc.rims.adhocgroupIDRC SUPPORTEDen

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IDRC Research Results / Résultats de recherches du CRDI
2010-2019 / Années 2010-2019
Research Results (Ecohealth) / Résultats de recherches (Écosanté)