Modeling strategies for controlling H1N1 outbreaks in China

dc.contributor.authorJin Zhang
dc.contributor.authorYanni Xiao
dc.date.accessioned2013-09-13T14:42:08Z
dc.date.available2013-09-13T14:42:08Z
dc.date.issued2012
dc.description.abstractThere has been a global attack of A/H1N1 virus in 2009, which widely affected the world’s normal stability and economic development. Since the emergence of the first diagnosed A/H1N1 influenza infected person in 11 May 2009 in China, very strict policy including quarantine and isolation measures were widely implemented to control the spread of this disease before the vaccine appeared. We propose a compartmental model that mimics the infection process of A/H1N1 under control strategies taken in mainland China. Apart from theoretical analysis, using the statistic data of Shaanxi Province, we estimated the unknown epidemiological parameters of this disease in Shaanxi via least-squares fitting method. The estimated control reproductive number of H1N1 for its first peak was Rc1 = 2.555 (95% CI: 2.362–2.748) and that for the second peak was Rc2 = 1.886 (95% CI: 1.765–2.001). Our findings in this paper suggest that neither quarantine nor isolation measures could be relaxed, and the implementation of these interventions can reduce the pandemic outbreak of A/H1N1 pandemic significantly.en
dc.formatTexten
dc.format.extent1 digital file (19 p. : ill.)en
dc.format.mimetypeapplication/pdf
dc.identifier.citationJin Zhang, & Yanni Xiao (2012). Modeling strategies for controlling H1N1 outbreaks in China. International Journal of Biomathematics, 5(4): 1-19.doi:10.1142/S1793524511001593en
dc.identifier.urihttp://hdl.handle.net/10625/51657
dc.language.isoen
dc.publisherWorld Scientific Publishing Companyen
dc.subjectA/H1N1 INFLUENZAen
dc.subjectQUARANTINEen
dc.subjectISOLATIONen
dc.subjectLEAST-SQUARES FITTINGen
dc.subjectVECTOR-BORNE DISEASESen
dc.subjectINFLUENZA A VIRUS, H5N1 SUBTYPEen
dc.subjectDISEASE CONTROLen
dc.subjectCHINAen
dc.titleModeling strategies for controlling H1N1 outbreaks in Chinaen
dc.typeJournal Article (peer-reviewed)en
idrc.copyright.holderWorld Scientific Publishing Company
idrc.dspace.accessIDRC Onlyen
idrc.noaccessDue to copyright restrictions the full text of this research output is not available in the IDRC Digital Library or by request from the IDRC Library. / Compte tenu des restrictions relatives au droit d'auteur, le texte intégral de cet extrant de recherche n'est pas accessible dans la Bibliothèque numérique du CRDI, et il n'est pas possible d'en faire la demande à la Bibliothéque du CRDI.en
idrc.project.componentnumber104519010
idrc.project.componentnumber104519018
idrc.project.number104519
idrc.project.titleInternational Research Chairs Initiative (IRCI)en
idrc.recordsserver.bcsnumberIC01-3412-167
idrc.rims.adhocgroupIDRC SUPPORTEDen

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