Processing and analysis of ChIP-seq data [Chinese language]

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dc.contributor.authorGao Shan
dc.contributor.authorZhang Ning
dc.contributor.authorLi Bo
dc.contributor.authorXu Shuo
dc.contributor.authorYe Yan-Bo
dc.contributor.authorRuan Ji-Shou
dc.date.accessioned2013-05-29T13:01:34Z
dc.date.available2013-05-29T13:01:34Z
dc.date.issued2012
dc.description.abstractThe next-generation sequencing coupled with chromatin immunoprecipitation (ChIP-seq) is becoming a key technology for the study of transcriptional regulation in the context of functional genomics. Due to the overwhelming amount of data generated from ChIP-seq experiments, the ChIP-seq data processing brings many new challenges in the field of bioinformatics. Considering the development of data processing skills largely behind that of the ChIP-seq experiment techniques, it is urgent to give a review on the ChIP-seq data processing for more and more oncoming researchers to build or improve algorithms. This paper provides a brief overview of the ChIP-seq data processing, highlighting the main prob-lems and methods in detail, to allow scientists to understand rapidly and deeply.en
dc.formatTexten
dc.format.extent1 digital file (12 p. : ill.)en
dc.format.mimetypeApplication/pdf
dc.identifier.citationS Gao Shan, Zhang Ning, Li Bo, Xu Shuo, Ye Yan-Bo, & Ruan Ji-Shou (2012). Processing and analysis of ChIP-seq data. HEREDITAS (Beijing), 34(6), 773-783.doi:10.3724/SP.J.1005.2012.00773en
dc.identifier.issn0253-9772
dc.identifier.urihttp://hdl.handle.net/10625/51229
dc.identifier.urihttp://www.chinagene.cn/Jwk_yc/EN/abstract/abstract20838.shtml
dc.language.isozh
dc.subjectNEXT GENERATION SEQUENCINGen
dc.subjectCHIP-SEQen
dc.subjectDATA PROCESSen
dc.subjectTRANSCRIPTION REGULATIONen
dc.subjectEPIGENETICSen
dc.subjectGENOMICSen
dc.subjectBIOINFORMATICSen
dc.titleProcessing and analysis of ChIP-seq data [Chinese language]en
dc.typeJournal Article (peer-reviewed)en
idrc.dspace.accessIDRC Onlyen
idrc.project.componentnumber104519010
idrc.project.number104519
idrc.project.titleInternational Research Chairs Initiative (IRCI)en
idrc.recordsserver.bcsnumberIC01-3412-121
idrc.rims.adhocgroupIDRC SUPPORTEDen

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