Poor thiamin and riboflavin status is common among women of childbearing age in rural and urban Cambodia

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dc.contributor.authorWhitfield, Kyly C.
dc.contributor.authorKarakochuk, Crystal D.
dc.contributor.authorLiu, Yazheng
dc.contributor.authorMcCann, Adrian
dc.contributor.authorTalukder, Aminuzzaman
dc.date.accessioned2015-02-26T17:50:15Z
dc.date.available2015-02-26T17:50:15Z
dc.date.copyright2015
dc.date.issued2015-01
dc.description.abstractBackground: Thiamin deficiency in infancy is the underlying cause of beriberi, which can be fatal without rapid treatment. Reports of thiamin deficiency are common in Cambodia; however, population representative data are unavailable. Because B-complex vitamin deficiencies commonly occur in combination, riboflavin was also investigated. Objective: We determined the biomarker status of thiamin and riboflavin in women of childbearing age in rural and urban Cambodia. Methods: We measured thiamin (erythrocyte thiamin diphosphate; TDP) and riboflavin (erythrocyte glutathione reductase activity coefficient; EGRac) status in a representative sample of Cambodian women (aged 20–45 y) in urban Phnom Penh (n = 146) and rural Prey Veng (n = 156), Cambodia, and, for comparison purposes, in a convenience sample of women in urban Vancouver, British Columbia, Canada (n = 49). Results: Thiamin insufficiency (TDP # 90nmol/L) was common among both urban (39%) and rural (59%) Cambodian women (P < 0.001), whereas <20% of Vancouver women were thiamin insufficient (P < 0.001). The prevalence of suboptimal and deficient riboflavin status (EGRac $ 1.3) was 89%, 92%, and 70% among women in Phnom Penh, Prey Veng, and Vancouver, respectively (P < 0.001). Conclusions: Suboptimal status of both thiamin and riboflavin were common in Cambodian women, with substantially higher rates among women living in rural Prey Veng than in urban Phnom Penh. Strategies may be needed to improve the thiamin and riboflavin status of women in Cambodia. The unexpected finding of high riboflavin inadequacy status in Vancouver women warrants further investigation.en
dc.formatTexten
dc.format.extent1 digital file (p. 1-6)en
dc.format.mimetypeapplication/pdf
dc.identifier.citationWhitfield, K.C., Karakochuk, C.D., Liu, Y., McCann, A., Talukder, A., Kroeun, H. , et al. (2015). Poor Thiamin and Riboflavin Status Is Common among Women of Childbearing Age in Rural and Urban Cambodia. The Journal of Nutrition, 1-6. doi:10.3945/jn.114.203604en
dc.identifier.urihttp://hdl.handle.net/10625/53789
dc.language.isoen
dc.publisherAmerican Society for Nutritionen
dc.subjectTHIAMINen
dc.subjectVITAMIN B-1en
dc.subjectRIBOFLAVINen
dc.subjectVITAMIN B-2en
dc.subjectERYTHROCYTE GLUTATHIONE REDUCTASE ACTIVITY COEFFICIENTen
dc.subjectEGRACen
dc.subjectMICRONUTRIENT DEFICIENCIESen
dc.subjectWOMENen
dc.subjectCAMBODIAen
dc.subjectCANADAen
dc.subjectWOMEN'S HEALTHen
dc.subjectNUTRITIONAL STATUSen
dc.titlePoor thiamin and riboflavin status is common among women of childbearing age in rural and urban Cambodiaen
dc.typeJournal Article (peer-reviewed)en
idrc.copyright.holderAmerican Society for Nutrition
idrc.dspace.accessIDRC Onlyen
idrc.noaccessDue to copyright restrictions the full text of this research output is not available in the IDRC Digital Library or by request from the IDRC Library. / Compte tenu des restrictions relatives au droit d'auteur, le texte intégral de cet extrant de recherche n'est pas accessible dans la Bibliothèque numérique du CRDI, et il n'est pas possible d'en faire la demande à la Bibliothéque du CRDI.en
idrc.project.componentnumber106928001
idrc.project.number106928
idrc.project.titleSmall-scale Aquaculture to Strengthen Food Security in Cambodia (CIFSRF)en
idrc.recordsserver.bcsnumberIC01-971-199
idrc.rims.adhocgroupIDRC SUPPORTEDen

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