Jorge, Marianna B.Loro, Vania L.Bianchini, AdaltoWood, Chris M.Gillis, Patricia L.2013-10-242013-10-2420122013Jorge, M.B.Loro, V.L., Bianchini, A., Wood, C.M., & Gillis, P.L. (2013). Mortality, bioaccumulation and physiological responses in juvenile freshwater mussels (Lampsilis siliquoidea) chronically exposed to copper. Aquatic Toxicology, 126, 137-147.doi:10.1016/j.aquatox.2012.10.0140166-445Xhttp://hdl.handle.net/10625/52020As little is known about the toxic mode of action and sub-lethal effects of copper exposure in freshwater mussels, the study examined physiological effects of long-term copper exposure (survival, growth, copper bioaccumulation, whole-body ion content, oxygen consumption, filtration rate, ATPase activities, and biomarkers of oxidative stress) in juvenile (6 month old) mussels (Lampsilis siliquoidea). Results indicate that ionoregulatory disruption in freshwater mussels chronically exposed to copper is the main mechanism of toxicity and that redox parameters do not appear to be useful as indicators of sub-lethal copper toxicity.Text1 digital file (p. 137-147)Application/pdfenCOPPER TOXICITYFRESHWATER MUSSELPHYSIOLOGICAL EFFECTSACUTE CHALLENGERECOVERYIONOREGULATIONJournal Article (peer-reviewed)