Yanhua QuRuiying ZhangPeng CuiGang SongZiyuan DuanFumin Lei2012-08-292012-08-292011Yanhua Qu, Ruiying Zhang, Peng Cui, Gang Song, Ziyuan Duan, & Fumin Lei (2011). Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v). Virology Journal, 8, 1-9.doi:10.1186/1743-422X-8-250http://hdl.handle.net/10625/50224There are ongoing health risks posed by the pandemic 2009 H1N1 influenza viruses. This research provides a detailed phylogenetic analysis in 394 sequences of H1N1 viruses, taken from swine, human and avian sources from 1918 to 2009, to estimate a temporal reconstruction of reassortment history of 2009 H1N1 viruses. H1N1 influenza viruses were first isolated from swine in 1930; in Europe, avian H1N1 viruses were first detected in pigs in 1979. Pigs have been considered a possible “mixing vessel” in which genetic material can be exchanged. There is a potential for novel progeny viruses to arise, to which humans would be susceptible.Text1 digital file (p. 1-9)Application/pdfenINFLUENZA IN HUMANSINFLUENZA A VIRUS, H5N1 SUBTYPEPHYLOGENYDISEASE TRANSMISSIONGENOMICSEPIDEMIOLOGYZOONOTIC DISEASESFAR EAST ASIASWINEGLOBAL HEALTHJournal Article (peer-reviewed)