Dengue immunopathogenesis : a cross talk between host and viral factors leading to disease : part I - Dengue virus tropism, host innate immune responses, and subversion of antiviral responses

Abstract

This detailed paper addresses the general features of the dengue virus (DENV) infections complex, including the virus structure and genome, epidemiology, and clinical outcomes. This is followed by an updated review of the literature describing the host innate immune strategies as well as the viral mechanisms acting against and in favor of the DENV replication cycle and infection.

Description

Two part article

Keywords

DENGUE, AEDES AEGYPTI, MOSQUITO-BORNE DISEASES, IMMUNOLOGY, PATHOGENESIS, DISEASE CONTROL, EPIDEMIOLOGY, ARBOVIRUS, LATIN AMERICA, GLOBAL SOUTH

Citation

DOI