Protein mass spectrometry detects multiple bloodmeals for enhanced Chagas disease vector ecology

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dc.contributor.author Keller, Judith I.
dc.contributor.author Lima-Cordón, Raquel
dc.contributor.author Monroy, M. Carlota
dc.contributor.author Schmoker, Anna M.
dc.contributor.author Zhang, Fan
dc.contributor.author Howard, Alan
dc.contributor.author Ballif, Bryan A.
dc.contributor.author Stevens, Lori
dc.date.accessioned 2019-09-05T16:12:34Z
dc.date.available 2019-09-05T16:12:34Z
dc.date.issued 2019-08-07
dc.identifier.issn 1567-1348
dc.identifier.uri http://hdl.handle.net/10625/57964
dc.description.abstract Ecohealth-based approaches have been recognized as a sustainable method of Chagas disease control. Bloodmeal data and vector prevalence of various hosts fosters an understanding of local vector ecology and behavior. This detailed paper provides validation of the ability to detect multiple bloodmeals using synthetic hemoglobin reference peptides (SRPs) that differ among the previously reported most common bloodmeals. The study shows the superior ability of hemoglobin peptide-based LC-MS/MS to detect and identify Chagas disease vector bloodmeal sources (of field-collected Triatomine vectors from Guatemala), compared to classical DNA-based polymerase chain reaction (PCR). en
dc.format.mimetype application/pdf
dc.language.iso en
dc.publisher Elsevier en
dc.subject ECOHEALTH en
dc.subject TRIATOMA en
dc.subject CHAGAS DISEASE en
dc.subject EPIDEMIOLOGY en
dc.subject DISEASE VECTORS en
dc.subject SPECTROMETRY en
dc.subject TAXONOMY en
dc.subject HEMOGLOBIN en
dc.subject GUATEMALA en
dc.subject LATIN AMERICA en
dc.subject NORTH AND CENTRAL AMERICA en
dc.title Protein mass spectrometry detects multiple bloodmeals for enhanced Chagas disease vector ecology en
dc.type Journal Article (peer-reviewed) en
idrc.project.number 106531
idrc.project.componentnumber 106531001
idrc.project.title Ecohealth Interventions for Chagas Disease Prevention in Central America en
idrc.copyright.holder © 2019 Elsevier B.V.
idrc.copyright.oapermissionsource MGC signed post January 2008 en
idrc.dspace.access Open Access en
idrc.rims.adhocgroup IDRC SUPPORTED en
dc.relation.journal Infection, Genetics and Evolution
idrc.recordsserver.bcsnumber IC36-1643402171-240995


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