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Modeling strategies for controlling H1N1 outbreaks in China

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dc.contributor.author Jin Zhang
dc.contributor.author Yanni Xiao
dc.date.accessioned 2013-09-13T14:42:08Z
dc.date.available 2013-09-13T14:42:08Z
dc.date.issued 2012
dc.identifier.citation Jin Zhang, & Yanni Xiao (2012). Modeling strategies for controlling H1N1 outbreaks in China. International Journal of Biomathematics, 5(4): 1-19.doi:10.1142/S1793524511001593 en
dc.identifier.uri http://hdl.handle.net/10625/51657
dc.description.abstract There has been a global attack of A/H1N1 virus in 2009, which widely affected the world’s normal stability and economic development. Since the emergence of the first diagnosed A/H1N1 influenza infected person in 11 May 2009 in China, very strict policy including quarantine and isolation measures were widely implemented to control the spread of this disease before the vaccine appeared. We propose a compartmental model that mimics the infection process of A/H1N1 under control strategies taken in mainland China. Apart from theoretical analysis, using the statistic data of Shaanxi Province, we estimated the unknown epidemiological parameters of this disease in Shaanxi via least-squares fitting method. The estimated control reproductive number of H1N1 for its first peak was Rc1 = 2.555 (95% CI: 2.362–2.748) and that for the second peak was Rc2 = 1.886 (95% CI: 1.765–2.001). Our findings in this paper suggest that neither quarantine nor isolation measures could be relaxed, and the implementation of these interventions can reduce the pandemic outbreak of A/H1N1 pandemic significantly. en
dc.format Text en
dc.format.extent 1 digital file (19 p. : ill.) en
dc.format.mimetype application/pdf
dc.language.iso en
dc.publisher World Scientific Publishing Company en
dc.subject A/H1N1 INFLUENZA en
dc.subject QUARANTINE en
dc.subject ISOLATION en
dc.subject LEAST-SQUARES FITTING en
dc.subject VECTOR-BORNE DISEASES en
dc.subject INFLUENZA A VIRUS, H5N1 SUBTYPE en
dc.subject DISEASE CONTROL en
dc.subject CHINA en
dc.title Modeling strategies for controlling H1N1 outbreaks in China en
dc.type Article en
idrc.project.number 104519
idrc.project.componentnumber 104519010
idrc.project.componentnumber 104519018
idrc.project.title International Research Chairs Initiative (IRCI) en
idrc.copyright.holder World Scientific Publishing Company
idrc.dspace.access IDRC Only en
idrc.rims.adhocgroup IDRC SUPPORTED en
idrc.recordsserver.bcsnumber IC01-3412-167
idrc.noaccess Due to copyright restrictions the full text of this research output is not available in the IDRC Digital Library or by request from the IDRC Library. / Compte tenu des restrictions relatives au droit d'auteur, le texte intégral de cet extrant de recherche n'est pas accessible dans la Bibliothèque numérique du CRDI, et il n'est pas possible d'en faire la demande à la Bibliothéque du CRDI. en


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