Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003–11) : a national observational cohort study

Date

2012-12

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

The World Health Organization (WHO) has recommended that antiretroviral therapy be offered to all HIV-infected individuals with uninfected partners of the opposite sex (serodiscordant couples) to reduce the risk of transmission. Whether a public health approach is feasible, and the outcomes are sustainable at a large scale and in a developing country setting, is assessed in this study. Results show that antiretroviral therapy in serodiscordant couples reduced HIV transmission across China, which suggests that the treatment-as-prevention approach is a feasible public health prevention strategy on a national scale. The durability and generalizability of such protection, however, needs to be further studied.

Description

Keywords

ANTIRETROVIRAL TREATMENT, HIV, CHINA, HIV PREVENTION, PUBLIC HEALTH, HEALTH INTERVENTION

Citation

Zhongwei Jia, Yuhua Ruan, Qianqian Li, Peiyan Xie, Ping Li, Xia Wang, et al. (2012). Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003–11): a national observational cohort study. The Lancet.doi:10.1016/S0140-6736(12)61898-4

DOI