Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003–11) : a national observational cohort study
Date
2012-12
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
The World Health Organization (WHO) has recommended that antiretroviral therapy be offered to all HIV-infected individuals with uninfected partners of the opposite sex (serodiscordant couples) to reduce the risk of transmission. Whether a public health approach is feasible, and the outcomes are sustainable at a large scale and in a developing country setting, is assessed in this study. Results show that antiretroviral therapy in serodiscordant couples reduced HIV transmission across China, which suggests that the treatment-as-prevention approach is a feasible public health prevention strategy on a national scale. The durability and generalizability of such protection, however, needs to be further studied.
Description
item.page.type
Journal Article (peer-reviewed)
item.page.format
Text
Keywords
ANTIRETROVIRAL TREATMENT, HIV, CHINA, HIV PREVENTION, PUBLIC HEALTH, HEALTH INTERVENTION
Citation
Zhongwei Jia, Yuhua Ruan, Qianqian Li, Peiyan Xie, Ping Li, Xia Wang, et al. (2012). Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003–11): a national observational cohort study. The Lancet.doi:10.1016/S0140-6736(12)61898-4