Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v)

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IDL-50224.pdf (1.76 MB)

Date

2011

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Publisher

BioMed Central

Abstract

There are ongoing health risks posed by the pandemic 2009 H1N1 influenza viruses. This research provides a detailed phylogenetic analysis in 394 sequences of H1N1 viruses, taken from swine, human and avian sources from 1918 to 2009, to estimate a temporal reconstruction of reassortment history of 2009 H1N1 viruses. H1N1 influenza viruses were first isolated from swine in 1930; in Europe, avian H1N1 viruses were first detected in pigs in 1979. Pigs have been considered a possible “mixing vessel” in which genetic material can be exchanged. There is a potential for novel progeny viruses to arise, to which humans would be susceptible.

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Keywords

INFLUENZA IN HUMANS, INFLUENZA A VIRUS, H5N1 SUBTYPE, PHYLOGENY, DISEASE TRANSMISSION, GENOMICS, EPIDEMIOLOGY, ZOONOTIC DISEASES, FAR EAST ASIA, SWINE, GLOBAL HEALTH

Citation

Yanhua Qu, Ruiying Zhang, Peng Cui, Gang Song, Ziyuan Duan, & Fumin Lei (2011). Evolutionary genomics of the pandemic 2009 H1N1 influenza viruses (pH1N 1v). Virology Journal, 8, 1-9.doi:10.1186/1743-422X-8-250

URI

http://hdl.handle.net/10625/50224

DOI

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IDRC Research Results / Résultats de recherches du CRDI
2010-2019 / Années 2010-2019
Research Results (Ecohealth) / Résultats de recherches (Écosanté)