Identification of malaria transmission and epidemic hotspots in the western Kenya highlands : its application to malaria epidemic prediction

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IDL-48170.pdf (1.26 MB)

Date

2011

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Publisher

BioMed Central, London, GB

Abstract

Conducted in five sites in the western Kenya highlands, two U-shaped valleys (Iguhu, Emutete), two V-shaped valleys (Marani, Fort-Ternan) and one plateau (Shikondi) for 16 months, this detailed study examines how highlands terrain affects exposure and sensitivity to malaria. It shows that V-shaped ecosystems, and the plateau ecosystem have very low malaria prevalence and few individuals with an immune response to two major malaria antigens. The U-shaped ecosystems are transmission hotspots. However, because V-shaped ecosystems have very low malaria prevalence and few individuals with an immune response, they can be considered as probable epidemic hotspots.

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Keywords

EPIDEMICS, VECTOR-BORNE DISEASES, VECTOR CONTROL, MALARIA, CLIMATE CHANGE, KENYA, HIGHLAND ECOSYSTEMS, CLIMATE VARIABILITY, DISEASE VECTORS, CLIMATE SENSITIVE DISEASES, SOUTH OF SAHARA, GEOGRAPHICAL ASPECTS, METEOROLOGICAL STATIONS

Citation

Wanjala, C. L., Waitumbi, J., Zhou, G., & Githeko, A. K. (2011). Identification of malaria transmission and epidemic hotspots in the western Kenya highlands: its application to malaria epidemic prediction. Parasites & Vectors, 4(1), 81. doi:10.1186/1756-3305-4-81

URI

http://hdl.handle.net/10625/48170

DOI

Collections

IDRC Research Results / Résultats de recherches du CRDI
2010-2019 / Années 2010-2019
East Africa / Afrique de l'Est
Health / Santé
Research Results (CCAA) / Résultats de recherches (ACCA)