Global Health Research Initiative (GHRI) operational research grants for the Canadian International Immunization Initiative (CIII2) : project title "development of novel vaccination strategies against helicobacter pylori in Latin America"; final technical report (May 30, 2004 - May 30, 2006)
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2006
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Abstract
Preliminary research suggests that H. pylon Lipopolysaccharide (LPS) phenotype falls within the previously reported Lewis xly classification with 3 % of strains being non-typeable. Interestingly, Lewis b occurs in over 20 % of strains tested. This is significant since North American H. pylon isolates lack Lewis a and Lewis b antigens and so far, these antigens were only reported in Asian isolates. The report describes a multidisciplinary research program aimed at identification of the optimal common LPS structure/s that can be utilized in the design of protective LPS-based conjugate vaccine in Latin America and Caribbean countries.
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IDRC Final Report
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Keywords
IMMUNIZATION, VACCINATION, DISEASE CONTROL, STRATEGIC PLANNING, CAPACITY BUILDING, LATIN AMERICA, METHODOLOGY, STATISTICAL ANALYSIS, PARTICIPATORY RESEARCH, CHILE, SOUTH AMERICA, CUBA, CANADA, GLOBAL HEALTH, HELICOBACTER PYLORI